Your total trip with all stops is around 1,000 miles / 1600 km, taking roughly 15.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Mississippi and District of Columbia.
Start from Mississippi (MS).
Birmingham, Alabama is stopping point #1 after driving about 240 miles (380 km) or 4 hours.
Chattanooga, Tennessee is stopping point #2 after driving about 150 miles (240 km) or 2 hours. Your total trip so far is about 390 miles or 620 km over roughly 6 hours of driving.
Roanoke, Virginia is stopping point #3 after driving about 370 miles (600 km) or 5.5 hours. Your total trip so far is about 760 miles or 1220 km over roughly 11.5 hours of driving.
Finally, District of Columbia (DC) is your destination after driving about 240 miles (390 km) or 4 hours. Your total trip with all stops is around 1,000 miles or 1600 km, taking roughly 15.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.